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LEADING OFF: DeGrom looks for 4-0 start at San Diego
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A look at what's happening all around the majors today:...

Castro homers, drives in 4 to help Astros rout Twins 16-4
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HOUSTON (AP) -- About a week ago Jason Castro was struggling at the plate, batting a paltry .114 and searching for answers to end his woes....

Holliday gives Cardinals 5-4 win over Phillies
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ST. LOUIS (AP) -- Matt Holliday delivered the St. Louis Cardinals' first walk-off win of the season on Wednesday night and then was mobbed by his teammates....

Big Papi hits 509th HR to power Red Sox past White Sox 5-2
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CHICAGO (AP) -- Boston Red Sox manager John Farrell shook his head and grinned when asked about the latest clutch hit and milestone home run by David Ortiz....

Sabathia, Yankees beat Orioles 7-0 to end 6-game skid
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BALTIMORE (AP) -- For a change, the New York Yankees did just about everything right....

Tampa Bay Rays hit 4 home runs and beat Dodgers 8-5
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ST. PETERSBURG, Fla. (AP) -- Steve Pearce hit one of four Tampa Bay homers, a go-ahead three-run shot in the sixth inning, and the Rays beat the Los Angeles Dodgers 8-5 on Wednesday night....

Martin delivers winning hit, Blue Jays beat Rangers 4-3
TORONTO (AP) -- Hits have been few and far between for Blue Jays catcher Russell Martin in 2016....

Stanton homers, Marlins hold on for 4-3 win
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MIAMI (AP) -- Giancarlo Stanton homered and drove in two runs for the Miami Marlins who held on for a 4-3 victory over the Arizona Diamondbacks on Wednesday night....

Kluber throws 5-hit shutout; Indians beat Tigers 4-0
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CLEVELAND (AP) -- Corey Kluber gave the Detroit Tigers two chances. Then he looked like a Cy Young Award winner....

Chatwood leads Rockies to 2-0 win, Padres' 8th shutout
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SAN DIEGO (AP) -- Tyler Chatwood's long road back from Tommy John surgery seemed a little shorter on Wednesday....